Year :

Legend Biotech Raises $150.5 Million in Series A Preferred Financing To Advance its Oncology Pipeline and Platform

Somerset, NJ, April 1, 2020 – Legend Biotech Corporation (Legend), a global, clinical-stage biopharmaceutical company engaged in the discovery and development of novel cell therapies for oncology and other indications, announced today that it has raised $150.5 million in Series A financing. Proceeds from the financing will be used to advance the research and development […]

Apr 01, 2020

Legend Biotech Announces Milestone Payment Achieved from the LCAR-B38M CAR-T Collaboration with Janssen

Piscataway, NJ, January 28, 2020 – Legend Biotech announced that, according to the terms and conditions of an agreement with Janssen Biotech, Inc. (Janssen), the fourth milestone payment has been achieved relating to the U.S. clinical development of the B-cell maturation antigen (BCMA) chimeric antigen receptor T-cell (CAR-T) therapy, LCAR-B38M (JNJ-68284528 (JNJ-4528)). “We are pleased […]

Jan 28, 2020

Updated Data from LEGEND-2, a Phase 1/2 Open-label Study of BCMA-Directed CAR-T Cell Therapy LCAR-B38M Show Long-term Responses, Safety Profile, and Complete Response Rate in Treatment of Patients with Advanced Relapsed or Refractory Multiple Myelomama

Orlando, FL, December 9, 2019 – Legend Biotech reported updated data on the LEGEND-2 (NCT03090659) Phase1/2 open-label, first-in-human study, which evaluated the investigational chimeric antigen receptor T-cell (CAR-T) therapy, LCAR-B38M, in the treatment of patients with advanced relapsed and/or refractory multiple myeloma (RRMM) in China. LCAR-B38M is a structurally differentiated CAR-T cell therapy containing a […]

Dec 09, 2019

Initial Data from Phase 1b/2 Study of BCMA-Directed CAR-T Cell Therapy JNJ-4528 Show Early and High Responses in Advanced Relapsed or Refractory Multiple Myeloma

Orlando, FL, December 7, 2019 – Legend Biotech announced today initial results from the Janssen Research &Development, LLC (Janssen)-sponsored Phase 1b/2 CARTITUDE-1 study (NCT03548207) evaluating the efficacy and safety of JNJ-68284528 (JNJ-4528), an investigational B-cell maturation antigen (BCMA)-directed chimeric antigen receptor T cell (CAR-T) therapy being evaluated in the treatment of patients with relapsed and/or […]

Dec 07, 2019

U.S. Food and Drug Administration Grants Breakthrough Therapy Designation for
JNJ-68284528, an Investigational BCMA CAR-T Cell Therapy

Designation based on the ongoing U.S. Phase 1b/2 CARTITIUDE-1 (MMY2001, NCT03548207) study in advanced relapsed or refractory multiple myeloma PISCATAWAY, NJ, DECEMBER 6, 2019 – Legend Biotech USA Inc. announced today that the U.S. Food and Drug Administration (FDA) has granted a Breakthrough Therapy Designation (BTD) to Janssen Research & Development, LLC (Janssen) for JNJ-68284528 (JNJ-4528), […]

Dec 06, 2019

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