Scientific Publications

Legend Biotech sponsors research with academic institutions to evaluate our agents. The manuscripts from this research are presented below.

Year :

Applying State-of-the-Art Survival Extrapolation Techniques to the Evaluation of CAR-T Therapies: Evidence from a Systematic Literature Review

Matthew Sussman, Concetta Crivera, Jennifer Benner & Nicholas Adair

Ciltacabtagene Autoleucel, a B-cell Maturation Antigen Directed Chimeric Antigen Receptor T-cell Therapy in Patients with Relapsed or Refractory Multiple Myeloma (CARTITUDE-1): a phase 1b/2 open-label study

JG Berdeja, D Madduri, SZ Usmani, A Jakubowiak, M Agha, AD Cohen, AK Stewart, P Hari, M Htut, A Lesokhin, A Deol, NC Munshi, E O’Donnell, D Avigan, I Singh, E Zudaire, TM Yeh, AJ Allred, Y Olyslager, A Banerjee, C Jackson, JD Goldberg, JM Schecter, W Deraedt, SH Zhuang, J Infante, D Geng, X […]

Comparative Effectiveness Research for CAR-T Therapies in Multiple Myeloma: Appropriate Comparisons Require Careful Considerations of Data Sources and Patient Populations

N Shah, M Sussman, C Crivera, S Valluri, J Benner, S Jagannath

Exploratory Trial of a Biepitopic CAR T-Targeting B Cell Maturation Antigen in Relapsed/Refractory Multiple Myeloma

J Xu, L-J Chen, S-S Yang, Y Sun, W Wu, Y-F Liu, J Xu, Y Zhuang, W Zhang, X-Q Weng, J Wu, Y Wang, J Wang, H Yan, W-B Xu, H Jiang, J Du, X-Y Ding, B Li, J-M Li, W-J Fu, J Zhu, L Zhu, Z Chen, F X-H Fan, J Hou, J-Y Li, […]

A Phase 1, Open-Label Study of LCAR-B38M, a Chimeric Antigen Receptor T Cell Therapy Directed Against B Cell Maturation Antigen, in Patients with Relapsed or Refractory Multiple Myeloma

W Zhao, J Liu, B Wang, Y Chen, X Cao, Y Yang, Y Zhang, F Wang, P Zhang, B Lei, L Gu, J Wang, N Yang, R Zhang, H Zhang, Y Shen, J Bai, Y Xu, X Wang , R Zhang, L Wei, Z Li, Z Li, Y Geng, Q He, Q Zhuang, X Fan, […]